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GP Clomiphene
Geneza Pharmaceuticals
1 x 30 tabs » 50 mg/tab
General information:
Manufacturer: Geneza Pharmaceuticals
: Clomiphene Citrate
Pack: 30
tabs (50 mg/tab)
Active Life: 5-7 days
Drug Class: Selective Estrogen Receptor Modulator
(Oral)
Average Dose: Men 50-100 mg/day
Acne: Yes
Water Retention:
No
High Blood Pressure: Rare
Liver Toxic: Low
Aromatization:
None
Decrease HPTA function: No, used to restore it
Strong gonadotropin
stimulator/mild anti-estrogen
GP Clomiphene Product Genuine on Geneza Pharmaceuticals
C
lomiphene
Citrate is not an anabolic steroid, but a prescription drug generally
prescribed to women as a fertility aid. This is due to the fact that clomiphene
citrate shows a pronounced ability to stimulate ovulation. This is accomplished
by blocking/minimizing the effects of estrogen in the body. To be more specific
Clomid is chemically a synthetic estrogen with both agonist/antagonist
properties, and is very similar in structure and action to Nolvadex. In certain
target tissues it can block the ability of estrogen to bind with its
corresponding receptor. Its clinical use is therefore to oppose the negative
feedback of estrogens on the hypothalamic-pituitary-ovarian axis, which enhances
the release of LH and FSH. This of course can help to induce
ovulation.
For athletic purposes, Clomid does not offer a tremendous
benefit to women. In men however, the elevation in both follicle stimulating
hormone and (primarily) luteinizing hormone will cause natural testosterone
production to increase. This effect is especially beneficial to the athlete at
the conclusion of a steroid cycle when endogenous testosterone levels are
depressed. If endogenous testosterone levels are not brought beck to normal, a
dramatic loss in size and strength is likely to occur once the anabolics have
been removed. This is due to the fact that without testosterone (or other
androgens), the catabolic hormone cortisol becomes the dominant force affecting
muscle protein synthesis (quickly bringing about a catabolic metabolism). Often
referred to as the post-steroid crash, it can quickly eat up much of your newly
acquired muscle. Clomid can play a crucial role in preventing this crash in
athletic performance. As for women, the only real use for Clomid is the possible
management of endogenous estrogen levels near contest time. This can increase
fat loss and muscularity, particularly in female trouble areas such as this hips
and thighs. Clomid however often produces troubling side effects in women
(discussed below), and is likewise not in very high demand among this group of
athletes.
Male users generally find that a daily intake of 50-100 mg (1-2
tablets) over a four to six week period will bring testosterone production back
to an acceptable level. A very common regime of dosing is; 300 md/day 1, 100
mg/day for days 2-11, and 50 mg/day for days 12-21. This raise in testosterone
should occur slowly but evenly throughout the period of intake. Since an
immediate boost in testosterone is often desirable, many prefer to combine
Clomid with HCG (Human Chorionic Gonadotropin) for the first week or two after
the steroids have been removed. The kick-start from HCG also helps to restore
the normal ability for the testes to respond to endogenous LH, which may be
hindered for some time after the cycle is ended due to a prolonged state of
inactivity. Once the HCG is stopped, the user continues treatment with Clomid
alone. HCG should not be used for longer than two or three weeks though, as the
resulting increased testosterone and estrogen levels may again initiate negative
feedback inhibition at the hypothalamus. When planning your ancillary drug
program, it is also important to remember that injectable steroids can stay
active for a long duration. Using ancillary drugs the first week after a long
acting injectable like Sustanon has been stopped may prove to be wholly
ineffective. Instead, the athlete should wait for two to three weeks, to a point
where androgen levels will be diminishing. Here the body will be primed and
ready to restore testosterone production.
Clomid and HCG are also
occasionally used periodically during a steroid cycle, in an effort to prevent
natural testosterone levels from diminishing. In many instances this practice
can prove difficult however, especially when using strong androgens for longer
periods of time. There is also no exact method for using the two drugs in this
manner. Some have experimented by periodically administering small doses of HCG
along with one or two tablets of Clomid, perhaps for a few days at a stretch
followed by a longer break. An on/off schedule would be implemented; for fear
that this combination may lose some effectiveness if used continuously for this
purpose. This method of intake may prove to be effective, although it is really
much more feasible to stimulate testosterone production after the cycle than to
try and maintain it for the long duration during.
In addition to helping
with the post-cycle testosterone crash, this drug can also help with elevated
estrogen levels during a steroid cycle. A high estrogen bevel puts an athlete in
serious risk of developing gynecomastia, which is an obvious unwanted side
effect. With the intake of Clomid, the athlete can hopefully reduce his risk for
developing gynecomastia. The estrogen "blocking" properties of Clomid appear to
be slightly weaker than Nolvadex in comparison however, which is why it is not
usually thought of as an equal substitute for estrogen maintenance. Of course
both drugs have similar actions in the body. and are relatively interchangeable
for this purpose. Clomid can likewise also be used as a maintenance
anti-estrogen throughout the duration of steroid cycle with good confidence,
just as is done with Nolvadex. In most instances this will prove equally
sufficient, the drug effectively minimizing the activity of estrogen in the body
and warding off gyno and excess water/fat retention. Unfortunately just as with
Nolvadex this is not always the case however, and many find it necessary to
addition another anti-estrogenic drug. The most common adjunct is Proviron, an
oral DHT used to competitively lower aromatase activity and raise the androgen
to estrogen ratio. The Clomid/Nolvadex and Proviron combination is extremely
effective, although we could alternately replace them both with a more specific
aromatase inhibitor such as Arimidex,Femara, or Aromasin. While stronger at
combating estrogen in most cases, these drugs are also typically much more
costly.
As for toxicity and side effects, Clomid is considered a very
safe drug. Bodybuilders seldom report any problems, but listed possible side
effects do include hot flashes, nausea, dizziness, headaches and temporarily
blurred vision. Such side effects usually only appear in females however, as
they feel the effects of estrogen manipulation much more readily than men. While
female athletes can clearly gain some benefit from this substance, estrogen
manipulation is probably not the most comfortable way to go about cutting up.
Should it still be used for such purposed and side effects do become pronounced,
the drug of course is to be discontinued and (at least) a break taken from
it.
Clomiphene citrate is widely
available on the black market in a variety of brand names as well as generic
tabs and liquid versions.